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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd939784fe4cadf53458406be49dfbf65c2fe547c4157c73e11c3f25f0ec93e36' 
  AND token = 'c8cOSj5WP6FGOdKL6DWKIu2x1VBQkLk7qB2g+n3wS20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}