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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e53bf5ac667e6b0cefad00e02c539f73c49d5b52c36ccb9d244de76ae049c935' 
  AND token = 'VrewNyqFlfuIKDWytJoSzv+4nC5W612fgu+eBKmHnzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}