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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fc3c66121b1cd2a823923b49f3968837216e9720891f4a25d07b777d7dbf89d' 
  AND token = 'IMPwCIzkzUWXn46qMMkT3zEwQdtA5cmcye/FliFu5So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}