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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c1dfc19adbfe47219262d8f80a56042481c079ed3c07c500ff144c33aefd432' 
  AND token = '7X19lXz7ja5kXOA43tV90cvX3a6NKwwiLxBOOQyoVGA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}