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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37d918e27300c284fe238e9faf29afab9ac53b98603b0215de0b687aed38e90e' 
  AND token = 'EmvPn83A+lrvWMPg2j0cW4qZG3LSOvAm7eSnms0djJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}