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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efcd41381534bde3c600657b664d8a89a36a7f9e08a4a0853e7e91f35b6aed3a' 
  AND token = '0GkhOZ+P7z7T4it5BJsN4+NBMV5zyniCx+Ia4g9bvKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}