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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5448fbfa9edc7d438a73d2178e8da3c8c8ba876da2ab9c11aa3b724991c28b7' 
  AND token = '9/Rr3qpAEnfC9AGFclmHFu8nTYPXrOYs7rJkc4xQp2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}