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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b799639a77862ccb65f3a49594971e22a81315520f64a594de1b7d122010f3af' 
  AND token = '2nvxEnznfKF6Gi7TXNyMWjTmr6e7dAp6nqz+R/V39DQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}