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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f4aee2da62394387fec4dcc8c82febc55a9d21c7006cc9baed1c5e6d0d3db4e' 
  AND token = 'tlgtdP5GgMkrrHkcbQFxPbj2s7z4VFiAFLtkNVKMihU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}