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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aadfe1360ca8e1e5376549906900d4d1af0dabf6eafb2f4d13beb4fd9819442' 
  AND token = '2zV4Ibs7rm/+dGTZN4+bL9dna9a38vdT7rNEiH1XvUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}