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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18f987280ec3cd8f90b392708a4699cd6c0cad6d9c552a1e00629699fb79cd3a' 
  AND token = 'lNFueCs0gIg1CAjnmsMJxachOU/B4HVwrOaOWepL8x0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}