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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f030a69e5e53e00afff567fca97e4dccd048d5296a08a0b8f6549d2a69bc754b' 
  AND token = '5EnbUftM/FG1bfSmJN8wr22ClfI5G24pN/Oe7Y2VKiI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}