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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '913006f40f35d29852dd7360c3b9ad5a0311d9b12c2ea841ccdd36926e6bb61c' 
  AND token = 'eGSF5vzV9DZMjgX3QFMTHpz4GgL50iCFDtwo6DbhmEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}