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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e9e7a3d43676f1f28a1e73bb15a7af20ced358f108d8b058b6cee24d3db6583' 
  AND token = '0Mnlrn8OMAp/HlH+MiMlubDyTaqAASuJvKkZQCtO9pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}