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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64ef9b1897bd54b674717d8656e285898f9b6a8ac5075ba0a07b64e7cb013115' 
  AND token = 'f+hy1Io2oDE4OeTSrm16F1JOMqg4BQ8Jy61wUPGNp1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}