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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e607aa4a71d6598f6855c6856f82a583d2c323d2d3bd8c7e4668244874556dd6' 
  AND token = 'qtbXK8V8VpF1gAxLd5qNO0vgluXYOFxeg+z8Obv9ZpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}