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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e024b788781a16cba49b6760fc84a59ba62236416ee28ce8b005a3332e2e2885' 
  AND token = 'B+mi/ScRRGlM7yybxcDFTYPo1PYf09uDqVXTJvhUhyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}