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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88b0e79f4cae57363d96f1cdd5d476e6c4f446379d8b79dd95b804530412e779' 
  AND token = 'SzLJ1ksU7GkU9L50PCoUpFdHGYlKRSoMsi9d/NrUSrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}