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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e39d7101b210c66eeea4078bc3a0e42a94eb468e4d184abe37197eba5a37758f' 
  AND token = 'p0+EwkGQeKZrEp1Y+AHQ3m/l9aaQ9u9Q00fQ5Pm43pA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}