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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c49c6c6943b7d7a093a55c9b9eb2d3e1e6483f9dbf1c832be9e49daa422e057c' 
  AND token = '4DXhh4TeDyCHEivhYsaKWG1SvbdMslPTrYWtciBnCdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}