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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc8c369bb07ba9395abfe2bbf1b52486c3a3ff9d97744fe1f1d71e496e34214a' 
  AND token = 'WuyOjlIoFxoTh600zkIAOpsRHlNG1+c7EIBNnnZVCps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}