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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '260901a5286ef442a716829a9c14eb64d3396a42937dee712a04e9fc87181a1c' 
  AND token = 'J146QG3cBBC2PTwtvw4eldAGY2/JN5p4hnpTSVW+Qi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}