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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3201c03acbe3dbf83019a04292d30cf4dc456f866646a6a686d0d9a1f4c072ee' 
  AND token = 'WoBgRgdelFu3LtOas4gcKXBtcvUZ4QLOIArcdky+1NM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}