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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0f6a048f27c30dc0249a92cc42c500b42db8637606a12cafd3fbe4ecdc22fb4' 
  AND token = 'kpg/lgIMc3fL+2iJUSoUqczAnuBNgsUNTLOWGQw4pg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}