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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7790c90899db34ae77231b34fecabaee08141c1b73eb54521153c4b6e7815d7c' 
  AND token = 'pC1K+Pf7+YKJvBb/zHbpLHoxbQB1ACIoGX3EwA3HWqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}