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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efb9f7ee372d17d3be5d9542b51e2a7e107055eff88883930e81554b3855c8af' 
  AND token = 'esweqL+SYQbnPNmWUOrrTrEHjiyZPIf6dNVV/1XW/5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}