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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3887fca5af519dd3619fe59ba775d16534014479a29b20af380c04e5b8b6776c' 
  AND token = 'qtKw7Z+9OrcZbSml/d2s1u/fFs27RF0k6e+6gpfhNd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}