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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea6d8f59763efbb5d023135253645f652255c4b40a5fefc372511991f2684e8b' 
  AND token = 'Vx+pXhL5sC7DNu4+PF9M0WPEGNexSoBXHm14eigVn08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}