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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a5fc5bc6ae0f30f94e85fea1287d76ef016df4552ce45b9e13b437af4a79cf1' 
  AND token = 'CYa/FFuA44RY0fH5lku6fKW9n5eNyc1B2GX3akjbQGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}