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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '401d0ec1b53ec7edce331bfb23ae4704b8c0a417e71ed849316febbb8ed21051' 
  AND token = '9DzVWk4Il+hvjL28a1VX6QxpFLGQ1QOLaIZE8Abv5bE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}