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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba8eeb3226163c8986abd41497afe953d0ccd4b5a3ac260acd8019d221c24f69' 
  AND token = 'PO/ydmiKkjXghl6RByul+I/edWTnbURWjdTpygXCJag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}