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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6061c71323e6379ceb96e1151048e1991b7eafb7880bfa9049c308910c99271f' 
  AND token = '+friD1IPtGXIE+vZOUAEEv9XaChHYJqnCSr1eHtzN70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}