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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81709956f71e5b82c22fba3f4df49f9e1111d652624d2968627ce68bbd9624db' 
  AND token = 'y3qksdCZYKNHdPUjucQ2btRny+yBLWpLNmNrvl/MAXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}