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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29ee108ce670685fafc1045493468bb2c0ffa54c3c619f8a4d500f28165161aa' 
  AND token = 'VeR5kZjBap09+ZypBM79cKlYNezc/znrck2kLpOft2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}