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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fed65f4eb511ecf57bec0a3c01a5043d540ed9d53d331aad20a956e33d9e8a85' 
  AND token = 'ghc3OTSniMHxQMy3TTpoz0VVzvjaB4rD40yoexXU9hU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}