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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48284b1a220d9ad19f7d655c372a335e1f8bb5b7393229a2181ddd601428d18f' 
  AND token = 'ZRAhGHB7fAd6h/THfgR8BQlNE05vAErAxDVlvwm5sy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}