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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95cccc03f2292af01f90befae4f5e0e446ec213233b2b221c403ee29d610dbb1' 
  AND token = 'vHa9YkBIOWU25UV549ajsSP12rGAwiV1NZsn9D6YUq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}