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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f8e5c010da3f3dda0fe607480c7b2abcc6dbe9ebf66e933bfb2d9a743274c2f' 
  AND token = '0RSW4MheH55ydkQU37syaZ+MGyL7bp9ou6CkHout/n4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}