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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cddb162997cfde95a24c81ff82c4e873294bfbd06298cb2237c5265e2948fbf6' 
  AND token = '9LIkDZKlNX+wuwrFAG4/h+ya+z27wTXIo4EULWXzkSc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}