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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4f4d448963ed2f99781c63c02989d6dbaf4859182e3c73d0abaaa5e4979e825' 
  AND token = '25d8TokBRAkPoJ+Mhk+zcmO9Bq6Gl4R/wLcuC1C+82g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}