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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '743aa41dad1e7ac5566818180fda1d2678e0a0963607197c6a4b3a67cf6c02d4' 
  AND token = 'h3ydrvvTNdaWK8I4xuBQpcLuE38UEuvWaBZhbjMXOik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}