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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b5c1fa641b5102af185a1fec93aff78ac8cb1b0ad899f13c9204231803d07e7' 
  AND token = 'Cu478GAZR8lCZcq9UFnmMfrY0HUpNtkn50L0eP2Nrq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}