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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '260210c9daa4ea77ac477fa4c80e9482f05bf2e2991103f155f8d1a94e3f5480' 
  AND token = 'GHmp3uac80qyn/GrZbudY4m4oXIhReq9fqAnf43Ls54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}