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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b59eb300dd59b07eb9f9b0cc9d23d3ed2b15da66dffe29919687db4fedc5a34' 
  AND token = 'BmfG4KXuByuO7mWha0Y40Z3vE7GUFdv0ZvXoPdx+Lys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}