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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cdafa95911e171b8784c5299f89ccdeb0e57288728e14a1be1dede4608fed79' 
  AND token = 'LP+L3C0MusQMiltmDkBU3+a1pIPgpjUrfb8tV7y8U6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}