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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50b9ed82356c7880425a73f0ff9c048b1c82ff94a309c0b141bb2b830cd8f52d' 
  AND token = 'iL7Xdi6BOg8wrsk3Si3MshlRvfLixGJi8auh2Tlt8kM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}