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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac20647d1b273c6d707e6adc66a36b1ea3b85b5c3b729504ccef2e7f429e21fc' 
  AND token = 'kImRU6LrN5xCQTY2LL4U8Uk2LozwPUXuep5by3nhjO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}