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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cace5789c49e57389249cd8ac169e7435ca25ef88595f3c5b040cd5d67c35de4' 
  AND token = 'UeNQvwFb0mt/gkaFFYXrqOq2z7HHmk9NJjCNzRn7WvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}