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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f9aa9947564f8f6dbec72d23138a2275d3bab46d07c025526c4a1fb6b9df6a1' 
  AND token = 'JXg8IQ9XWt6AFYCcbgDaOq2P1MitBaz9uU2GoNxs7o8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}