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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '891679ce3b689918f9e401d19a373ded81b6c8208acf565d158317b6566f7162' 
  AND token = 'ecs3xFExbg3z48LRQwaLWlRo0O+lLKS9Dv2Yivo1VLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}